We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
Read More
9
Magnesium reduces mortality in HFpEF
Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
9
HERG activators show promise for LQT2
Molecular insights into the rescue mechanism of an HERG activator against severe LQT2 mutations.
We explored the potential of ICA-105574, an HERG activator, to combat severe mutations that cause long QT syndrome type 2 (LQT2). Using both animal models and cellular simulations, we found that ICA-105574 effectively shortened QT intervals and restored critical potassium currents in cellular models with specific HERG mutations. Our results indicate that compounds like ICA-105574 could be valuable in treating LQT2, and that advanced simulations can aid in designing future HERG activators.
Read More
Most Useful Reviews
9
Supports heart performance
215 people found this helpful
Taurine, magnesium, and potassium work beautifully together! Taurine aids in transporting these minerals and improving blood circulation and cardiac metabolism. In heart failure, taurine loss can lead to potassium excretion from the heart muscle, causing serious issues. By supplementing taurine, these irreversible effects can be mitigated, lowering blood pressure and strengthening heart muscles. Potassium helps all body muscles, including the myocardium, while magnesium controls heartbeat rhythm and prevents arrhythmia. This blend is far superior to panangin available in pharmacies.
Read More
9
Miracle vitamins
40 people found this helpful
I originally purchased these vitamins for my husband’s leg cramps, and they worked wonders. I then tried them for my own heart health and nervous stability, and the results exceeded expectations. I can breathe easier now with this magnesium, potassium, and taurine complex. My grandmother, too, benefited from them for her heart and joints. Her blood pressure normalised, and her neck pain eased. I highly recommend consulting a doctor, but these vitamins are a miracle!
Read More
9
Improves heart function
25 people found this helpful
I've taken this supplement for three years to strengthen my heart muscle during seasonal courses. After just a month, I felt significantly better: my pulse regularised, sleep improved, and blood pressure stabilised. I recommend it to women over 40, provided there are no contraindications.
We explored how magnesium supplementation might influence mortality rates in patients with heart failure and preserved ejection fraction (HFpEF). The study involved nearly 2,000 patients, with careful matching to ensure a fair comparison between those receiving magnesium and those who weren’t.
Interestingly, we found that magnesium intake was linked to a significant reduction in 28-day mortality rates. This effect was most notable in older adults, women, and patients with high blood pressure. Despite these positive findings, magnesium treatment did lead to longer hospital and ICU stays.
Overall, magnesium shows promise as a supportive treatment for HFpEF, but further investigation is necessary to better understand its benefits and implications.
Read More
9
HERG activators show promise for LQT2
Molecular insights into the rescue mechanism of an HERG activator against severe LQT2 mutations.
We explored the potential of ICA-105574, an HERG activator, to combat severe mutations that cause long QT syndrome type 2 (LQT2). Using both animal models and cellular simulations, we found that ICA-105574 effectively shortened QT intervals and restored critical potassium currents in cellular models with specific HERG mutations. Our results indicate that compounds like ICA-105574 could be valuable in treating LQT2, and that advanced simulations can aid in designing future HERG activators.
Read More
9
Potassium channels reduce arrhythmia risk
Targeted M-Channel Activation in the Left Stellate Ganglion Protects Against Ischemia-Induced Ventricular Arrhythmias in Canines.
We explored the effects of activating M-type potassium channels in the left stellate ganglion to reduce heart issues caused by acute myocardial ischemia in beagles.
After treating some dogs with retigabine before inducing ischemia, we found that this activation significantly lowered sympathetic overactivity and cardiac irregularities.
The treated group showed increased resistance to dangerous arrhythmias and better heart rhythm stability compared to those who received a placebo. Overall, targeting these potassium channels might offer a new way to manage heart arrhythmias linked to ischemia.
Read More
9
Taurine shows limited cardiac benefit
Taurine and enzymatically modified isoquercitrin protected against methotrexate-induced deteriorations in the conductivity and rhythmicity of the heart in rats: Antioxidant, anti-inflammatory, and histological architecture approach.
We explored how taurine (Tau) and enzymatically modified isoquercitrin (EMIQ) may protect the heart from damage caused by methotrexate (MTX), a common cancer treatment. In our study with adult male rats, we divided them into different groups to assess various treatments against MTX-induced heart issues.
Although MTX disrupted heart function and increased heart rhythm problems, we observed that both Tau and EMIQ helped maintain heart conductivity and rhythm. The combination of these treatments provided the best results, but individually, they did not show sufficient benefits to combat MTX’s negative effects on heart health alone.
Read More
9
Taurine shows promise in PCC
Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition.
We explored the connection between plasma taurine levels and symptoms in individuals experiencing post-COVID condition (PCC). Our analysis included 117 patients during their COVID-19 hospitalization and six months later, comparing results to healthy controls.
Higher taurine levels were linked to reduced PCC symptoms and fewer adverse events. Importantly, those with rising taurine levels during recovery showed a significant decrease in negative clinical outcomes.
These findings suggest that taurine could be an important marker and potential treatment avenue worth investigating further in larger clinical trials.
Taurine, magnesium, and potassium work beautifully together! Taurine aids in transporting these minerals and improving blood circulation and cardiac metabolism. In heart failure, taurine loss can lead to potassium excretion from the heart muscle, causing serious issues. By supplementing taurine, these irreversible effects can be mitigated, lowering blood pressure and strengthening heart muscles. Potassium helps all body muscles, including the myocardium, while magnesium controls heartbeat rhythm and prevents arrhythmia. This blend is far superior to panangin available in pharmacies.
Read More
9
Miracle vitamins
40 people found this helpful
I originally purchased these vitamins for my husband’s leg cramps, and they worked wonders. I then tried them for my own heart health and nervous stability, and the results exceeded expectations. I can breathe easier now with this magnesium, potassium, and taurine complex. My grandmother, too, benefited from them for her heart and joints. Her blood pressure normalised, and her neck pain eased. I highly recommend consulting a doctor, but these vitamins are a miracle!
Read More
9
Improves heart function
25 people found this helpful
I've taken this supplement for three years to strengthen my heart muscle during seasonal courses. After just a month, I felt significantly better: my pulse regularised, sleep improved, and blood pressure stabilised. I recommend it to women over 40, provided there are no contraindications.
Read More
9
Alleviated palpitations
21 people found this helpful
An excellent product! I've tried many magnesium supplements, some of which caused side effects, but this one is fantastic. It effectively erased my anxiety and heart palpitations while also improving my mood stability. It has even helped ease PMS stress. This is my second order—I'm sold!
Read More
9
Supports heart health
13 people found this helpful
This remedy is perfect for maintaining heart and blood vessel health. Given that it can be challenging to obtain all necessary nutrients, magnesium and potassium are fundamental for everyone. This product ensures you receive essential support for cardiovascular wellbeing.
Heart disease refers to a range of conditions that affect the heart's function and overall health. This umbrella term includes various cardiovascular issues such as coronary artery disease, which is caused by the buildup of plaque in the arteries; heart rhythm problems (arrhythmias); and heart defects present at birth (congenital heart defects). Additionally, heart disease encompasses conditions related to the heart muscle, such as cardiomyopathy, and the heart's valves, which might not open or close properly. The effects of heart disease can be significant, impacting not only physical health but also quality of life, making prevention and timely medical intervention crucial.
Several risk factors contribute to the development of heart disease, including high blood pressure, high cholesterol levels, diabetes, obesity, poor diet, physical inactivity, and smoking. Genetics also play a role, as heart disease can run in families. To mitigate the risks, healthcare professionals typically recommend lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and avoiding tobacco use. For those already diagnosed with heart disease, treatment options can vary widely, ranging from lifestyle modifications to medications and, in severe cases, surgical interventions. Understanding the nature of heart disease and its risk factors is an essential step toward prevention and effective management.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is an essential mineral that plays a critical role in cardiovascular health. Research suggests that adequate magnesium intake may help reduce the risk of heart disease by maintaining normal heart rhythm, regulating blood pressure, and supporting overall vascular health. Some studies have shown that higher magnesium levels are associated with lower rates of heart attack and stroke, indicating that this mineral might have a protective effect on the heart. Additionally, magnesium helps with the transport of potassium and calcium, both of which are vital for proper heart function.
However, while magnesium supplementation may benefit those who are deficient, it is important to note that it should not be seen as a standalone treatment for heart disease. Individuals with existing heart conditions should consult their healthcare providers before making any changes to their diet or supplementation regimen. Overall, maintaining a balanced diet rich in magnesium through food sources like leafy greens, nuts, seeds, and whole grains, combined with regular physical activity, may contribute to better heart health.
Based on user reviews, the timeframe for noticing results from this heart health supplement can vary, but many users report improvements within a few weeks of consistent use. For example, one user noted feeling better after just a month, experiencing improvements in pulse regularity and blood pressure stability Read Review. Another user indicated that significant improvements were noticed in just 10-12 days of use, with mornings feeling more active and cheerful Read Review.
Several reviewers emphasized that this supplement not only aided their heart health but also had beneficial effects on related issues like muscle cramps and sleep disturbances. For instance, reports mention a reduction in heart palpitations and improved overall wellbeing within a short period of taking the supplement Read Review. While individual experiences may vary, it's clear that many users have found noticeable benefits relatively quickly, making it a popular choice for those seeking to support their heart health.
Magnesium supplementation shows considerable promise in supporting heart health, particularly in relation to heart disease. A study involving over 94,000 veterans found that those who took magnesium supplements had a lower risk of developing heart failure compared to nonusers, with just 8.0% versus 9.7% experiencing heart failure respectively [1]. Additionally, higher serum magnesium levels have been associated with reduced mortality from heart-related conditions in patients with chronic kidney disease [2]. Furthermore, magnesium intake has been linked to improved blood sugar control in individuals with coronary artery disease, suggesting a beneficial role in managing conditions that may contribute to heart disease [3].
However, while these studies indicate potential benefits, they do not establish magnesium as a definitive treatment for heart disease. There remain calls for further randomized controlled trials to bolster these preliminary findings, as some research also raises concerns about potentially increased mortality associated with elevated magnesium levels in certain hospital settings [13]. Overall, while magnesium supplementation is supported by some scientific evidence for its effects on heart health, especially in specific populations or conditions, caution and consultation with healthcare providers are advised before starting any new supplement regimen.
Based on user reviews, many individuals have reported significant improvements in their heart health and related symptoms after using this supplement. Notably, users highlighted enhanced cardiac function, with one individual mentioning a decrease in heart palpitations and improved pulse regularity within just a month of use Read Review. Another reviewer noted a remarkable decrease in the frequency of extrasystoles after shifting from another supplement, indicating that their heart rhythm became more stable Read Review.
Moreover, several users experienced broader benefits, such as reduced anxiety, improved sleep quality, and alleviation of muscle cramps. One user even reported feeling more energetic and cheerful in the mornings just 10-12 days into taking the supplement Read Review. Additionally, others emphasized the calming effect this complex has had on their general wellbeing, showcasing it as a multifaceted solution for both cardiovascular support and overall health enhancement Read Review. It's important to remember that individual results may vary, and one should consult a healthcare professional for personalized advice.
Based on user reviews, many individuals have reported positive experiences when combining this heart health supplement with other supplements for managing heart disease. For example, one user mentioned that taking a combination of these capsules with arginine and taurine resulted in no irregular heartbeats, while also noting an alleviation of anxiety Read Review. Another reviewer stated a significant improvement in pulse rates by taking the supplement alongside Coenzyme Q10 at night, suggesting a synergistic effect on overall cardiovascular health Read Review.
Users emphasized the essential role of the active ingredients—magnesium, potassium, and taurine—in promoting heart function and stabilization when combined appropriately. Several comments highlighted that these minerals paired together can enhance absorption and effectiveness, particularly in addressing issues like arrhythmia, muscle cramps, and overall nervous stability Read ReviewRead Review. Overall, the reviews suggest that combining this supplement with others can lead to improved outcomes for users dealing with heart-related concerns, though it's recommended to consult with a healthcare professional for personalized advice.
Users report various effective doses and preferences for magnesium in the context of heart health. Many individuals highlight that a combination of magnesium and potassium, sometimes with taurine, provides significant benefits in managing heart conditions. For instance, one user reported taking two capsules at night with a light meal, which helped alleviate side effects from medication, improve sleep quality, and enhance overall heart function Read Review. Similarly, another reviewer mentioned taking one capsule daily, resulting in a notable decrease in heart rhythm irregularities Read Review.
Moreover, many testimonials emphasize that magnesium is essential for regulating heartbeat and blood pressure, with several users advocating for its use in conjunction with potassium for optimal heart health. A consistent theme across reviews is the importance of consulting with a healthcare provider before starting any supplements, particularly for individuals over 50 or those already managing existing health conditions Read Review. Overall, users advocate for tailored doses based on individual health needs and professional recommendations.
9
Improves heart function
25 people found this helpful
I've taken this supplement for three years to strengthen my heart muscle during seasonal courses. After just a month, I felt significantly better: my pulse regularised, sleep improved, and blood pressure stabilised. I recommend it to women over 40, provided there are no contraindications.
8
Improves activity levels
7 people found this helpful
I've noticed a difference after using this effective drug for my cardiac muscle support. After about 10-12 days, my mornings have become more active and cheerful, with no discomfort in the heart area post-exercise.
9
Alleviated palpitations
21 people found this helpful
An excellent product! I've tried many magnesium supplements, some of which caused side effects, but this one is fantastic. It effectively erased my anxiety and heart palpitations while also improving my mood stability. It has even helped ease PMS stress. This is my second order—I'm sold!
9
Reduced extrasystoles
7 people found this helpful
On my cardiologist's advice, I tried Panangin but saw little improvement. However, with this new drug, I'm thrilled as the frequency of extrasystoles has significantly declined. I now take one capsule daily.
9
Irregular heartbeat relief
1 people found this helpful
I began taking this product with arginine and taurine two weeks ago due to rapid heartbeat and irregular rhythms. There have been no irregular heartbeats since I started. Additionally, this product may ease anxiety. An excellent product, especially when combined.
7.5
Reduced pulse rate
37 people found this helpful
Excellent results! I have congenital heart issues, and since I started taking this supplement, I've noticed my pulse rate has dropped significantly. I take it with Q10 at night and am very satisfied with the overall effect.
9
Supports heart performance
215 people found this helpful
Taurine, magnesium, and potassium work beautifully together! Taurine aids in transporting these minerals and improving blood circulation and cardiac metabolism. In heart failure, taurine loss can lead to potassium excretion from the heart muscle, causing serious issues. By supplementing taurine, these irreversible effects can be mitigated, lowering blood pressure and strengthening heart muscles. Potassium helps all body muscles, including the myocardium, while magnesium controls heartbeat rhythm and prevents arrhythmia. This blend is far superior to panangin available in pharmacies.
9
Essential minerals trio
1 people found this helpful
A wonderful trio of potassium, magnesium, and taurine! These essential substances are needed to protect and support the heart. Their use is very effective in hot weather and for women during blood loss—the complex effectively alleviates heartbeat issues and cramps.
7.5
Improved sleep quality
19 people found this helpful
Magnesium and potassium are essential for heart function. I found unexpected benefits while treating my autoimmune disease with prednisolone, which caused side effects like sleep disturbance and cramps. The Magnesium & potassium aspartate helped alleviate my cramps and improved my bowel function. I've noticed significant enhancements in my sleep as well. I take two capsules at night with a light meal; they are the right size and easy to swallow. I rate this product highly for its exceptional quality, and it will be a constant in my orders.
9
Heart support for elderly
9 people found this helpful
Perfect for those over 50! This supplement contains magnesium and potassium in easily absorbable forms. Magnesium is vital for glucose metabolism and energy production, while potassium aids many intracellular reactions, lowering stroke risk. It's an excellent choice for supporting heart health and includes taurine, which may improve insulin sensitivity.
7
Magnesium supplements lower heart failure risk
Nonprescription Magnesium Supplement Use and Risk of Heart Failure in Patients With Diabetes: A Target Trial Emulation.
We examined how magnesium supplements might influence heart failure and serious heart-related issues in diabetic patients.
In a study involving over 94,000 veterans, we found that those taking magnesium supplements experienced a lower risk of heart failure compared to nonusers. Specifically, 8.0% of supplement users developed heart failure, versus 9.7% of nonusers.
Furthermore, magnesium intake was linked to a reduced chance of major adverse cardiac events. However, it’s important to note that these findings need further investigation through randomized controlled trials.
8
Magnesium levels and heart disease mortality
Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5.
We examined the link between serum magnesium levels and the risk of death from heart failure, coronary heart disease, and stroke in patients with chronic kidney disease who don’t require dialysis. Over a decade, we followed 1,271 patients, noting that those with higher magnesium levels experienced significantly lower mortality rates from these conditions.
This suggests that maintaining adequate magnesium levels may help improve health outcomes for individuals with advanced kidney issues and an increased risk of cardiovascular problems.
7
Magnesium improves blood sugar control
Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease.
We investigated the effect of magnesium and calcium on blood sugar levels in 11,934 patients with coronary artery disease. Our findings indicated that higher serum magnesium levels and a favorable magnesium to calcium ratio were associated with lower abnormal HbA1c levels, which reflect better blood sugar management. In contrast, calcium showed no significant association with HbA1c levels. Importantly, we found no evidence that inflammation played a role in this relationship. Overall, magnesium might be beneficial for maintaining healthy blood sugar levels in those with heart disease.
4
Magnesium levels linked to mortality
Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database.
We examined how changes in serum magnesium levels affect in-hospital mortality for patients experiencing acute myocardial infarction (AMI). This study analyzed data from 2,716 AMI patients in the MIMIC database.
Surprisingly, we found that higher magnesium levels upon ICU admission and within the first 48 hours were linked to increased mortality rates. Regardless of age, gender, or severity scores, this trend persisted, suggesting that monitoring magnesium levels closely could be crucial for improving patient outcomes in the hospital setting.
References
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Moyano-Peregrin C, Rodelo-Haad C, Martín-Malo A, Muñoz-Castañeda JR, Ojeda R, et al. Upper normal serum magnesium is associated with a reduction in incident death from fatal heart failure, coronary heart disease and stroke in non-dialysis patients with CKD stages 4 and 5. Clin Kidney J. 2025;18:sfae390. doi:10.1093/ckj/sfae390
Dong H, Lu N, Wang J, Hu P. Serum magnesium, not calcium, is inversely associated with abnormal HbA1c concentrations in adults with coronary artery disease. Asia Pac J Clin Nutr. 2025;34:104. doi:10.6133/apjcn.202502_34(1).0010
Song L, Ying J, Li M, Ying L, Zhao C. Propensity score matched cohort study on magnesium supplementation and mortality in critically ill patients with HFpEF. Sci Rep. 2025;15:1944. doi:10.1038/s41598-025-85931-1
Sun L, Du J. Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018. Magnes Res. 2024;37:61. doi:10.1684/mrh.2024.0528
Song Q, Song L, Liu H, Tan H, Yang B, et al. Association of magnesium intake with predicted atherosclerotic lesions and cardiovascular risk in young adults based on PDAY score: a cross-sectional study. BMC Public Health. 2024;24:3232. doi:10.1186/s12889-024-20785-2
Behers BJ, Behers BM, Stephenson-Moe CA, Vargas IA, Meng Z, et al. Magnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length. Nutrients. 2024;16. doi:10.3390/nu16213617
Jiang Y, Luo B, Chen Y, Lu W, Peng Y, et al. Serum calcium-magnesium ratio at admission predicts adverse outcomes in patients with acute coronary syndrome. PLoS One. 2024;19:e0313352. doi:10.1371/journal.pone.0313352
Wyss C, Gündling PW, Kostev K. Real world effectiveness of Hawthorn special extract WS 1442 in a retrospective cohort study from Germany. Sci Rep. 2024;14:22986. doi:10.1038/s41598-024-74325-4
Seguchi M, Aytekin A, Xhepa E, Haude M, Wlodarczak A, et al. Vascular response following implantation of the third-generation drug-eluting resorbable coronary magnesium scaffold: an intravascular imaging analysis of the BIOMAG-I first-in-human study. EuroIntervention. 2024;20:e1173. doi:10.4244/EIJ-D-24-00055
Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
Copp KL, Steffen LM, Yi SY, Lutsey PL, Rebholz CM, et al. Magnesium-rich diet score is inversely associated with incident cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. Eur J Prev Cardiol. 2025;32:386. doi:10.1093/eurjpc/zwae251
Zhuang J, Zhang Q, Wang H, Su PH, Chen PY. Association between short-term changes in serum magnesium and in-hospital mortality following acute myocardial infarction: a cohort study based on the MIMIC database. Magnes Res. 2024;37:45. doi:10.1684/mrh.2024.0517
Fruh V, Babalola T, Sears C, Wellenius GA, Webster TF, et al. Dietary Minerals and Incident Cardiovascular Outcomes among Never-Smokers in a Danish Case-Cohort Study. Int J Environ Res Public Health. 2024;21. doi:10.3390/ijerph21070932
Tao J, Wang J, Peng H, Yuan Y, Lai H, et al. Association between serum phosphate, magnesium, calcium and aortic valve sclerosis: a propensity score-matched case-control study. Acta Cardiol. 2024;79:522. doi:10.1080/00015385.2024.2379682
Zhang J, Sun D, Guo Y, Tong J, Liu Q, et al. Targeted delivery of black phosphorus nanosheets by ROS responsive complex hydrogel based on angiogenesis and antioxidant promotes myocardial infarction repair. J Nanobiotechnology. 2024;22:433. doi:10.1186/s12951-024-02685-0
Kumawat A, Tavazzani E, Lentini G, Trancuccio A, Kukavica D, et al. Molecular insights into the rescue mechanism of an HERG activator against severe LQT2 mutations. J Biomed Sci. 2025;32:40. doi:10.1186/s12929-025-01134-w
Peng JQ, Zhou MM, Xu L, Wang X, Tang YH, et al. Targeted M-Channel Activation in the Left Stellate Ganglion Protects Against Ischemia-Induced Ventricular Arrhythmias in Canines. J Am Heart Assoc. 2025;14:e039059. doi:10.1161/JAHA.124.039059
Gregorio C, Barbati G, Scagnetto A, Lenarda AD, Ieva F. Wavelet-Mixed Landmark Survival Models for the Effect of Short-Term Changes of Potassium in Heart Failure Patients. Biom J. 2025;67:e70043. doi:10.1002/bimj.70043
Ukachukwu CU, Jimenez-Vazquez EN, Salwi S, Goodrich M, Sanchez-Conde FG, et al. A PAS-targeting hERG1 activator reduces arrhythmic events in Jervell and Lange-Nielsen syndrome patient-derived hiPSC-CMs. JCI Insight. 2025;10. doi:10.1172/jci.insight.183444
Tzang CC, Lin WC, Lin LH, Lin TY, Chang KV, et al. Insights into the cardiovascular benefits of taurine: a systematic review and meta-analysis. Nutr J. 2024;23:93. doi:10.1186/s12937-024-00995-5
Mahmoud MM, El-Batran SA, Hegazy R, El-Sayed WM. Taurine and enzymatically modified isoquercitrin protected against methotrexate-induced deteriorations in the conductivity and rhythmicity of the heart in rats: Antioxidant, anti-inflammatory, and histological architecture approach. J Appl Toxicol. 2024;44:1924. doi:10.1002/jat.4682
Khoramjoo M, Wang K, Srinivasan K, Gheblawi M, Mandal R, et al. Plasma taurine level is linked to symptom burden and clinical outcomes in post-COVID condition. PLoS One. 2024;19:e0304522. doi:10.1371/journal.pone.0304522
Li Y, Gao YN, Zhu YB, Lu WF, Yu JY, et al. Taurocholic acid ameliorates hypertension through the activation of TGR5 in the hypothalamic paraventricular nucleus. Food Funct. 2024;15:5088. doi:10.1039/d4fo00808a
Bkaily G, Simon Y, Abou Abdallah J, Ouertane C, Essalhi A, et al. Short Communication: Taurine Long-Term Treatment Prevents the Development of Cardiac Hypertrophy, and Premature Death in Hereditary Cardiomyopathy of the Hamster Is Sex-Independent. Nutrients. 2024;16. doi:10.3390/nu16070946
Jacques D, Bkaily G. Taurine Prevents Angiotensin II-Induced Human Endocardial Endothelium Morphological Remodeling and the Increase in Cytosolic and Nuclear Calcium and ROS. Nutrients. 2024;16. doi:10.3390/nu16050745
Dai T, Yan F, Gong J, Liu S. Anti-heart failure mechanism of saponin extract of black ginseng based on metabolomics. J Pharm Biomed Anal. 2023;236:115738. doi:10.1016/j.jpba.2023.115738
Li C, Zhou Y, Niu Y, He W, Wang X, et al. Deficiency of Pdk1 drives heart failure by impairing taurine homeostasis through Slc6a6. FASEB J. 2023;37:e23134. doi:10.1096/fj.202300272R
Brethel S, Locker S, Girens R, Rivera P, Meurs K, et al. The effect of taurine supplementation on the renin-angiotensin-aldosterone system of dogs with congestive heart failure. Sci Rep. 2023;13:10700. doi:10.1038/s41598-023-37978-1
Razzaghi A, Choobineh S, Gaeini A, Soori R. Interaction of exercise training with taurine attenuates infarct size and cardiac dysfunction via Akt-Foxo3a-Caspase-8 signaling pathway. Amino Acids. 2023;55:869. doi:10.1007/s00726-023-03275-4